IL10 producing regulatory T cells support fecal microbiota transplant (FMT)-mediated clearance of <i>Clostridioides difficile</i>Infection

Step-up fecal microbiota transplantation (FMT) strategy

Gut dysbiosis is a characteristic of inflammatory bowel disease (IBD) and is believed to play a role in the pathogenesis of IBD. Fecal microbiota transplantation (FMT) is an effective strategy to restore intestinal microbial diversity and has been reported to have a potential therapeutic value in IBD. Our recent study reported a holistic integrative therapy called "step-up FMT strategy," which ...

Ethical aspects of Fecal Microbiota Transplantation (FMT).

The importance of human microbiota in preserving human organism healthy is nowadays well acknowledged. The alteration of the microbiota can be the consequence of a persistent use of antibiotics or immunosuppressive medications or abdominal irradiation or surgery, wrong diet, or can be caused by surgery or anatomical condition. These alterations can cause many infections and diseases that today ...

Oral, frozen fecal microbiota transplant (FMT) capsules for recurrent Clostridium difficile infection

BACKGROUND Fecal microbiota transplantation (FMT) has been shown to be safe and effective in treating refractory or relapsing C. difficile infection (CDI), but its use has been limited by practical barriers. We recently reported a small preliminary feasibility study using orally administered frozen fecal capsules. Following these early results, we now report our clinical experience in a large c...

TREATMENT OF OBESITY BY IMPROVING THE METABOLISM OF OBESE PEOPLE BY FECAL MICROBIOTA TRANSPLANTATION (FMT) AND FECAL CAPSULES (SYSTEMATIC REVIEW)

Background: Over the past half-century, the prevalence of obesity and related metabolic disorders such as fat disorders, cardiovascular disease, myocardial infarction and stroke have increased dramatically. Various types of organisms, including bacteria, fungi, protozoan, and viruses, have evolved to live in the human gut, called microbiota. Scientists have found that thin people have a balance...

Factors Affecting Effectiveness of Fecal Microbiota Transplant